Department of Basic Medical Sciences

Department of Basic Medical Sciences

Basic medical sciences lay strong foundation for subsequent clinical learning. It is an integral part of medical and dental curriculum. Dental students have Anatomy, Physiology, and Biochemistry during their 1st year course and Pharmacology, Pathology, and Microbiology in 2nd year curriculum. Study of Basic Medical Sciences makes it easier for students to understand the clinical subjects and for better comprehension of the signs and symptoms of the diseases. Basic Medical sciences departments of Madha Dental College, helps students to have a clear understanding and knowledge of the normal anatomy, physiological functions and biochemical reactions in their first year of dentistry and etiological agents of microbial infections, their pathological manifestations and their pharmacotherapeutic management in their second year of dentistry. Background foundation of basic sciences helps them in their better understanding of clinical sciences and improves their clinical acumen.

OVERVIEW OF THE DEPARTMENT:

GOALS:

To accomplish the highest standard and to be a Centre of excellence in imparting sound knowledge in the field of Basic Medical Sciences to incline the students of dentistry into more skillful and competent dental professionals.

OBJECTIVES:

To provide an insight into the discipline of Basic Medical Sciences with effective practical-oriented teaching sessions and innovative approaches to ameliorate the quality of academic performance.
To inculcate comprehensive knowledge in the subjects of Basic Medical Sciences with a strong foundation for a better understanding of dental perspectives at the level of Undergraduate and Postgraduate students.
To augment the importance of scientific research among the students and keep them motivated to attend various conferences, CDEs and workshops to update their knowledge of recent advancements in the field of Basic Medical Sciences.

HIGHLIGHTS

KEY FEATURES

CORE COMPETENCIES / THRUST AREAS

LATEST AWARDS, ACHIEVEMENTS, EVENTS

FACILITIES

Programs

Department of Anatomy serves as a paving stone for the future doctors. Our department aims to inculcate extensive knowledge of anatomy to the students in relevant to dentistry and to develop a benchmark in education involving macroscopic, microscopic & developmental aspects of Human form.
Anatomy department at Madha Dental college comprises of a dissection hall with 10 dissection tables, skeletons, appropriate ventilation, adequate light source better to accommodate 100 students. There are separate rooms for cadaver storage tanks and specimen storage. Students are taught with adequate prosecuted parts and bones to gain deep insight about the anatomy of head & neck. Museum is well arranged with dry and wet specimens, embryology models and charts for better understanding.

ANATOMY

Physiology forms the basis for understanding how the body functions in health and disease. At its core, physiology explores the intricate mechanisms by which cells, tissues, organs, and organ systems interact to maintain homeostasis, and students gain profound insights into phenomena such as metabolism, circulation, respiration, digestion, and sensory perception, illuminating essential principles.
“In the experimental sciences, the greatest discoveries are often made by accident. But in physiology, it is by design.” – Claude Bernard.
Physiology plays a crucial role in the education and practice of dental students. Understanding the physiological mechanisms underlying oral health and disease is essential for diagnosing and treating dental conditions effectively. Moreover, an understanding of pain physiology is essential for managing patient discomfort during dental procedures.
The Department of Physiology in Madha Dental College imparts foundational knowledge to first-year dental students, familiarizing them with routine hematology tests such as determining bleeding time and clotting time.
Additionally, students receive instruction and hands-on practice in performing general examinations and measuring blood pressure, equipping them with essential skills for routine patient care in dental practice.
Overall, the Department of Physiology provides the foundational knowledge that dental students need to comprehend the biological processes involved in oral health and disease, enabling them to deliver comprehensive and effective dental care to their patients.

PHYSIOLOGY

The Department of Biochemistry at Madha Dental College and Hospital aims to provide a strong foundation for students pursuing dentistry with the necessary insights into the structure and functions of biomolecules, cells, and tissues.

This Department equips the first-year BDS students to enhance their practical skills, helping them to learn the fundamental principles, structures, and functions that govern biological systems at the molecular level. This knowledge is crucial for comprehending the molecular basis of health and diseases, which enables students to make effective decisions in the provision of patient care in dental settings.

BIOCHEMISTRY

Pathology, often called the study of diseases. It is a branch of science that deals with structural and functional changes in diseases, which present with clinical signs and symptoms. It is a discipline that provides diagnostic information to patients and clinicians. Department of pathology focuses training students to identify the cellular changes and helps them to become well-versed in haematology, urology investigations.

PATHOLOGY

The Department of Microbiology at Madha Dental College and Hospital focuses on unveiling the significance of important microbes in dentistry. The Department plays a vital role in inculcating II year B.D.S students the importance of sterilization and disinfection, a profound understanding of different infectious diseases in the oral cavity and their etiological agents.

Also, the importance of biomedical waste management, hand hygiene protocols, knowledge of a broad array of medically important microorganisms and the emergence of antibiotic resistance among microbes are greatly emphasized by the department.

MICROBIOLOGY

Pharmacology encompasses all aspects of knowledge about drugs, but most importantly those that are relevant to effective and rational use of drugs in daily clinical practice. There are two main branches of pharmacology, Pharmacokinetics and pharmacodynamics.

Other than learning Pharmacology, second year Dental students of Madha Dental College will prepare and dispense mouth washes, tooth paste and tooth powder in their practical lab hours and identify and understand the new drugs with their therapeutic effects and adverse effects.

PHARMACOLOGY

LAB

Faculty

Dr. Vidyalakshmi. K, M.Sc, Ph.D,

Professor of Pharmacology, Teaching experience- 25 years

Dr. R. Deepa M.Sc., M.Phil., Ph. D

Associate Professor of Biochemistry, Teaching Experience - 16 years

Dr. Savitha Niren. M.Sc., Ph. D

Associate Professor of Physiology, Teaching Experience - 16 years

Dr. A. Kiruthiga, M.Sc., Ph. D

Associate Professor of Microbiology, Teaching Experience: 13 years

Dr.S. Abilasha Msc, PhD (Anatomy), MBA(HM)

Associate Professor of Anatomy, Teaching experience; 9 Years and 5 months

Ms. A. Iswarya , M.Sc

Lecturer of Microbiology, Teaching Experience: 2 years 8 months

ONGOING RESEARCH

S No Title of the projects Principal Investigator

PUBLICATIONS

AWARDS & ACHIEVEMENTS

2024

September 2024

Dr. Savitha N, Department of Physiology, won the Best presentation (Faculty category) in the International Conference conducted by the Department of Physiology, Saveetha Dental College, Chennai on the 10th and 11th of September 2024

July 2024

Dr. Savitha Niren has secured the Copyright (ROC) certificate for Bainbridge reflex

2023

August 2023 - Dr. Abhilasha D

Dr. Abhilasha D Presented a scientific paper & won best paper in Biocon 2023 conducted by Department of Biotechnology at Sastra University on 7th August 2023.

November 2022

Dr. Deepa R, Department of Biochemistry

Dr. Deepa Rajendiran, won the Best Paper Presentation Award in 2022 for her oral presentation titled 'Antidiabetic and Antioxidant Activity of Mimosa pudica Extract in High-Fat Diet STZ-Induced Type 2 Diabetic Rat Model' at the International Conference on 'Recent Advances in Research and Innovations in Life Sciences,' held from 17-19 November 2022.

STUDENTS AWARDS

September 2024

Dr. A. Kiruthiga contributed as a Resource Person in “ONE DAY WORKSHOP ON PROCESSING AND CHARACTERIZATION OF CLINICAL SAMPLES” on 14/09/2024 organized by the Department of Microbiology at St. Anne’s Arts and Science College during the academic year 2024-2025.

July 2024

Dr. R. Deepa and Dr. Savitha Niren served as JUDGE in the 11th SAVEETHA TRANSDISCIPLINARY ANNUAL RESEARCH STAR SUMMIT held at SAVEETHA DENTAL COLLEGE AND HOSPITAL held between the 5th of July – 11th July 2024

June 2024

Dr. Savitha Niren Participated as a delegate in the National seminar on “Respiratory Adaptation to Extremes of Barometric Pressure” held on 28th June 2024

April 2024

Dr. Vidyalakshmi. K, Professor & HOD, Department of Pharmacology Contributed as a Resource person in the Basic medical sciences seminar entitled ‘‘Pharmacotherapy of Thyroid Disorder held on 27th April 2024 at Meenakshi Ammal Dental College and Hospital, Chennai, 600095

February 2024

Dr Vidyalakshmi K, Professor of Pharmacology has completed two days Research writing workshop and also received GCP certificate.

September 2023

Dr. Abilasha participated as a judge in ANATCON 2023 organised by the department of Anatomy held at Saveetha dental college & hospitals on 19th September 2023.

August 2023 - Dr. Kiruthiga A

Dr. Kiruthiga A, Associate Professor, Microbiology was Invited as a Judge in SCIENTIFIC SESSION OF THE BASIC SCIENCE CONFERENCE- ENVISION’23 held on 18th & 19th August 2023 at Sri Venkateshwara Dental College and Hospital, OMR, Thalambur, Chennai

July 2023

Dr Vidyalakshmi was invited for a guest lecture on OTC drugs in Dr MGR Educational and Research Institute. Chennai.

March 2023

Dr. Abhilasha Served as chair person in a International conference conducted by Amrita Vishwa Vidyapeetham university on March 24 2023

July 2022

Dr. R. Deepa, Department of Biochemistry, was invited as a Chairperson for the Virtual National Interdisciplinary Conference on ‘Global Emerging Trends in Science, Commerce, Humanity, and Education,’ held on 10th July 2022. The conference was organized by the Welfare Forum for Universal Research Scholars and Professors, managed by Kanishk Chavda Education and Charitable Trust, Junagadh, Gujarat.

Events & Scientific Presentations

18.11.2022

Basic Medical Sciences Departments organized a ‘‘National Seminar on Fundamentals of Research Publications’’ held on 18.11.2022 at Auditorium, Madha Dental College and Hospital.

PUBLICATION DETAILS

DEPARTMENT OF ANATOMY

 Dr ABILASHA

  1. Therapeutic Strategies in Oral Cancer – A Review. Research Journal of Pharmacy and Technology. 2024; 17(3):1398-2.
  2. Decoding Nanomedicine in Tackling Cardiovascular Diseases; Reaching the Unreached”. PriMera Scientific Medicine and Public Health 4.5 (2024): 03-09.
  3. Morphometric analysis of human occipital condyle in certain skulls of South India. International journal of Bio Medicine. Volume 32, Issue 4, 2012.
  4. Dermatoglyphics: a predictor tool to analyze the occurrence of breast cancer. International Journal of Medical Research & Health Sciences. Volume 3, Issue 1, 2014.
  5. Molecular docking analysis of alkaloid compounds with beta-catenin towards the treatment of colon cancer. International Journal of Bio Information. Volume 16, Issue 3, 2020.
  6. Docking analysis of importin-11 homology model with the phyto compounds towards colorectal cancer treatment. International Journal of Bio Information. Volume 16, Issue 2, 2020.
  7. Molecular docking anaylsis of Stevioside with Akt and PPARγ. International Journal of Bio Information. Volume 17, Issue 1, 2021.
  8. Stevioside attenuates insulin resistance in Skeletal muscle by facilitating IR/IRS1/Akt/GLUT4 signaling pathways: An in vivo and in silico approach. International Journal of molecules. Volume 26, Issue 24, 2021.
  9. Exploring craniofacial diversity in South Indian adults: an innovative investigation utilizing a dataset of 2000 orthopantomogram images. International journal of Chelonian Conservation and biology. Volume 18, Issue 2, 2023.
  10. A Comprehensive Morphometric Analysis of Mandibular Variations: Unveiling Novel Insights through Advanced Techniques. Journal of Advanced Zoology. Volume 44, Issue S2, 2023.
  11. Orthopantomogram insights: Dental pathology analysis in a South Indian adult cohort. British Journal of Psychotherapy. Volume 39, Issue 4, 2023.
  12. Anatomical Variations in Mandibular Canal Location: Implications for Prosthodontic Treatment Planning in the South Indian Population. Journal of Advanced Zoology. Volume 44, Issue S2, 2023.
  13. Antioxidant and anti-inflammatory properties of Rhodiola Roseananoparticles in an in vitro model. Journal of Korean academy of Psychiatric and mental health nursing. 2023;5(4).
    1. Anatomical variation in Mandibular angle region: Insights from Dry mandible studies. International Neurology journal. Volume 27, Issue 4, 2023.

    BOOK PUBLICATIONS:

    Intellectual property rights, ISBN: 978-93-5850-602-0, JEC Publishers: Jan, 2024.

     

    DEPARTMENT OF BIOCHEMISTRY

    Dr R. DEEPA

    1. Therapeutic Strategies in Oral Cancer – A Review. Research Journal of Pharmacy and Technology. 2024; 17(3):1398-2.
    2. Decoding Nanomedicine in Tackling Cardiovascular Diseases; Reaching the Unreached”. PriMera Scientific Medicine and Public Health 4.5 (2024): 03-09
    3. Protective Effect of Psidium guajava Leaf Extracts on Altered Carbohydrate Metabolism in Streptozotocin-Induced Diabetic Rats. Journal of Dietary Supplements, 2013;10(4):335–344.
    4. Antioxidants in Periodontal Diseases.Critical Review in Pharmaceutical Sciences. 2013;2(2):7-12.
    5. Phytochemical analysis and in-vitro activities of ethanolic leaf extract of Mimosa pudica. Indian Journal of Current Research. (ISSN NO: 2347-9213) 2015; 2:5-10.
    6. Potential Antidiabetic Effect of Mimosa pudica Leaves Extract in High Fat Diet and Low Dose Streptozotocin-Induced Type 2 Diabetic Rats. International Journal of Biology Research.2017;2(4):55-62.
    7. Hepatoprotective activity of ethanol extract of Mimosa pudica leaves in type 2 diabetic rats. The Pharma Innovation Journal 2018; 7(12): 223-226.
    8. A review on role of Antioxidants in diabetes. Asian Journal of Pharmaceutical and Clinical Research, 2018; 11(2):48-53.
    9. Dose-dependent antidiabetic effect of Mimosa pudica leaves extract in type 2 diabetic rat model. The Pharma Innovation Journal 2019; 8(3): 01-04.
    10. Drug-induced oral adverse reactions: a review. International Journal of Current Advanced Research 2019; 8(10(B)): 20158-20163.
    11. A Questionnaire-Based Survey on COVID-19 Knowledge & awareness among allied Health Sciences (AHS) students in Chennai. World journal of pharmacy and pharmaceutical sciences.2020; 9(12) :1016-1028.
    12. A phytopharmacological review on an endangered magical herb- Picrorhiza kurroa. Journal of Emerging Technologies and Innovative Research, 2021; 8(12):159-173.
    13. Oxidative Stress and Diabetes Mellitus – A Review. International Journal of Multidisciplinary Educational Research, 2022; 11(10):35-39.
    14. Preliminary Screening and evaluation of Commiphora Caudata Leaf extract on cariogenic pathogens. International Journal of Pharmaceutical Sciences and Research. 2022;13(10):4159-4165.
    15. An update on influenza – a deadly seasonal viral infection. World Journal of Pharmaceutical Research.2022;11(15):556-566.
    16. A Questionnaire-Based study to assess the awareness of harmful effects associated with junk foods consumption among adolescent. Asian Journal of Pharmaceutical and Clinical Research.2023:16(1):49-52.
    17. Histoarchitectural and Biochemical Evaluation of Isoproterenol-Induced Myocardial Ischemia in Heart & Lungs – An Experimental Dose – Dependent Study. Journal of Pharmaceutical Sciences and Research. May 2023;14(5):2329-2336.
    18. A Review on Stem Cells of Placenta. Biolife, 2023;11(2):18- 20.
    19. Need-Based Changes in Undergraduate Pharmacology Teaching in Dental College – A Survey on Student Perspective. Eur. Chem. Bull. 2023;12(12): 720-732.
    20. Preliminary Phytochemical screening and Antioxidant properties of Methanolic root extract of Picrorhiza kurroa. Research Journal of Pharmacy and Technology 2023; 16(9):4266-0.

    BOOK CHAPTERS PUBLICATIONS:

    1. Cardio protective role of Curcumin. Current Trends in biological sciences, Thanuj International Publishers. 2022;173-179.
    2. Current updates on angina pectoris- A deadly oxygen thirst of the heart. Current Research in Life Sciences.2023 ;1-13.
    3. Therapeutic Potential of Mimosa pudica– A review. Recent trends of innovations in chemical and biological sciences, Bhumi Publishing.2023;76-83.
    4. Antidiabetic potential of Indian medicinal plants-A review. Recent Research in Biosciences. 2023;234-245.
    5. Cerebellar Ataxia. Recent Research in Biosciences, Thanuj International Publishers. 2023;214-218.
    6. Role of BCL2 and ERK 1 / 2 in Myocardial Ischemia. Recent Research in Biosciences. India: Thanuj International Publishers. 2023; 20- 30.
    7. Diabetes mellitus and Infectious diseases. Recent Research in Biosciences. India: Thanuj International Publishers. 2023:219-223.
    8. A Review of Placenta and Umbilical Cord for Deriving Stem Cells and Their Function. Innovations In Environment, Health & Medical Research.2023;31-35.
    9. The PI3K/AKT Signaling Pathway in Type 2 Diabetes mellitus. Current Advances in Biosciences. India: Thanuj International Publishers. 2023; 9-19.
    10. Demystifying Midas touch by bacteria – Gold Biomineralization in Cupriavidus metallidurans. Dr. R. B. Tripathi, Dr. R. Deepa, Dr. A. Kiruthiga. (Eds), Current Advances in Biosciences. India: Thanuj International Publishers. 2023; 59-66.
    11. Vitamin D and Periodontal disease. Current Advances in Biosciences. India: Thanuj International Publishers. 2023; 221-230.
    12. Dental pulp stem cells and its applications in regenerative medicine. Current Advances in Biosciences. India: Thanuj International Publishers. 2023;165-183.
    13. Nanotechnology in Medicine. Current Advances in Biosciences. India: Thanuj International Publishers. 2023;391-398.

    BOOK EDITOR / REVIEWER:

    • Served as an editor for the book entitled “Current Advances in Biosciences” published by Thanuj International Publishers (ISBN: 978-93-94638-64-8, First edition, September 2023) Tamil Nadu, India.
    • Reviewer for Elsevier’s Textbook “Nutrition for Nurses” by Sreemathy Venkatraman, Published in May 2019 (ISBN:978-81-312-5479-0).

     

    DEPARTMENT OF MICROBIOLOGY

    Dr. A. KIRUTHIGA

    1. Decoding Nanomedicine in Tackling Cardiovascular Diseases; Reaching the Unreached. PriMera Scientific Medicine and Public Health 4.5. 2024;03-09.
      1. Improved detection of esp, hyl, asa1, gelE, cylA virulence genes among clinical isolates of Enterococci. BMC Res Notes. 2020 Mar 20;13(1):170.
      2. Higher Incidence of Pristinamycin Resistance among Enterococcus Faecium with iMLSB/cMLSB Phenotype. Biomed Pharmacol J 2020;13(1).
      3. Mechanisms of intrinsic antibiotic resistance in enterococci. Drug invention today. 2020;13(6).
      4. Fosfomycin Susceptibility among Urinary Enterococcus faecalis with High Level Aminoglycoside and Glycopeptide Resistant Phenotypes. Indian Journal of Public Health Research & Development. 2019 Dec;10(12): 970 – 974.
      5. High Level Aminoglycoside Resistance in Clinical Isolates of Enterococci. Indian Journal of Public Health Research & Development. 2019 Nov 1;10(11) : p2938
      6. Molecular characterization of high level aminoglycoside resistant non-urinary isolates of Enterococcus Int Journal Infect Dis 2016;45S:109.
      7. Clinico-microbiological investigation of catheter associated urinary tract infection by Enterococcus faecalis: vanA genotype. Journal of Clinical and Diagnostic Research.2015;9(8):DD05–DD05.

      BOOK CHAPTER PUBLICATIONS:

      1. Served as an editor for the book entitled “Current Advances in Biosciences” published by Thanuj International Publishers (ISBN: 978-93-94638-64-8, First edition, September 2023) Tamil Nadu, India.
      2. Oral dysbiosis – A potential decoder of systemic diseases, Recent Research in Biosciences, Apr-23, 140-144,
      3. Exploring the era of essential oils against Oral pathogens – Revisited, Current Advances in Biosciences, Sep-23, 20-32. ISBN: 978-93-94638-64-8, Thanuj International Publishers (Edition – 1: September, 2023).
      4. Demystifying Midas touch by bacteria – Gold Biomineralization in Cupriavidus metallidurans, Current Advances in Biosciences, Sep-23, 59-66. ISBN: 978-93-94638-64-8, Thanuj International Publishers (Edition – 1: September, 2023).
      5. Parasitic infestations of the Human Oral Cavity – Intruders unveiled, Current Advances in Biosciences, Sep-23, 67-77. ISBN: 978-93-94638-64-8, Thanuj International Publishers (Edition – 1: September, 2023).

      Ms. A. ISWARYA

      1. Detection of Colistin Resistance in Uropathogenic Carbapenem Resistant Klebsiella pneumoniae. Asian Pacific Journal of Health Sciences, 2022, 9(1), 156–157.
      2. A Study on Phenotypic Association between Biofilm and Drug Resistant Klebsiella Species Isolated from Urinary Tract Infections, J Clin of Diagn Res. 2021, 15(6), DC38-DC42.
      3. Phytochemical Assay, Cytotoxicity and Antibacterial Activity of Selected Indian Medicinal Plants for Bioprinting Applications, Trends in Biomaterials & Artificial Organs, 2022, Vol 36, p36

       

      DEPARTMENT OF PHARMACOLOGY

       DR. VIDYALAKSHMI.K

      1. Antinociceptive Effect of Certain Dihydroxy Flavones in Mice, Pharmacology Biochemistry and Behaviour, 2010; 96:1-6.
      2. Antioxidant Property of Plumbagin on Fibrosarcoma Induced Rats, Recent Research in Science and Technology, 2010,2(11):01-03.
      3. Anti-inflammatory Effect of Certain Dihydroxy Flavones and The Mechanisms Involved, Anti-inflammatory and Anti-allergy Agents in Medicinal Chemistry, 2012;11:253-261.
      1. Effect Of Dihydroxy Flavones on Morphine Tolerance, International Journal of Life Science and Pharma Research Vol-2,2012,173-177.
      2. Antinociceptive Effect of Certain Dimethoxy Flavones In Mice, European Journal of Pharmacology 727 (2014) 148–157
      3. Effect Of Indazole and Its Derivatives on Aspirin Induced Gastric Ulcer in Rats, International Journal of Pharmaceutical Sciences Review and Research 40(2) September – October 2016, Article No. 02, Pg. 28-32
      4. Opuntia ficus-indica extract as a potential therapeutic agent in methotrexate-induced hepatotoxicity: involvement of nrf2/ho-1 and pparγ pathways, Romanian Journal of Diabetes, Nutrition and Metabolic Diseases, 2023: volume, 30, Issue 4.

       

      BOOK CHAPTER PUBLICATIONS

      1. Piper longum and its hepatoprotective role – A review, Advances in Pharmaceuticals and Biosciences research, Thanuj International Publishers, First Edition, 2023; 109-115.
      2. Orphan Drugs- High priced Miracle Medicines, Advances in Pharmaceuticals and Biosciences research, Thanuj International Publishers, First Edition, 2023; 85-92.
      3. Efficient and reliable health care with -Artificial Intelligence, Advances in Pharmaceuticals and Biosciences research, Thanuj International Publishers, First Edition, 2023; 93-108.

       

      DEPARTMENT OF PHYSIOLOGY

      Dr T. SAVITHA NIREN

      1. Acacetin Interacts with Glycolytic Enzymes and Inhibits Diabetes. Texila International Journal of Public Health. Special Issue 2024;DOI: 10.21522/TIJPH.2013.SE.24.03.Art004.
      2. 2. Fabrication and Characterization of a Novel Dental Filling Herbal Composite Using Biphasic Calcium Phosphate and Leaf Extracts of Cassia occidentalis. Texila International Journal of Public Health Special Issue-2024 DOI: 10.21522/TIJPH.2013.SE.24.03.Art014

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